In some studies, CASC11 has been found to regulate tumor growth, invasion, metastasis, and apoptosis through its interaction with different microRNAs, carcinogenic proteins, carcinogens, and transcription factors.[7] In addition, CASC11 has also been implicated in coronary heart disease and osteoporosis.[8–20] Recent studies have revealed abnormal expression of CASC11 in different solid tumors and its involvement in cell proliferation, metastasis, invasion, apoptosis, and chemotherapy resistance, all of which have significant implications for tumor prognosis. Here, CASC11 is linked to osteoporosis.