Furthermore, other studies have shown that high CASC11 expression can markedly improve the drug resistance of malignant tumors, whereas knockdown CASC11 can reduce the drug resistance of cancer cells to chemotherapy drugs and improve the sensitivity of cancer cells to chemotherapy drugs.[23] Overall, all these studies indicate that CASC11 could act as a poor prognostic indicator of malignant tumors, which was consistent with the results of this study. Here, CASC11 is linked to cancer.