IL17A and autoimmune disease: Intermediate monocytes represent the most pro-inflammatory subtype within the monocyte population, and their perturbation has been documented in various inflammatory and autoimmune diseases.[3–5] Recent studies have concurrently indicated that the primary secretory factor of interleukin-17 (Th17), interleukin-17 (IL-17), plays a dual role in the process of alveolar bone resorption.