TNFRSF11B and scoliosis: OPG is a potential protective factor for scoliosis (Folkersen 2020 OR = 0.739, 95% CI = 0.611–0.893, P = .002; Zhao 2023 OR = 0.833, 95% CI = 0.716–0.968, P = .017).The results of Meta-analysis also showed OPG (P = 1.428e−4) would reduce the risk of scoliosis.