TNFRSF11A and scoliosis: When scoliosis was exposure, P < 5e−8 failed to extract SNPs, so we narrowed the P-value to 5e−7 and extracted 3 SNPs (rs1244564, rs140463745, and rs17178928) used as a means of determining the causal effect of scoliosis on OPG, RANKL, and RANK levels, and all SNPs used for MR analysis met the F-statistic values > 10.