FOLH1 and Familial prostate cancer: Thus, it is believed that fused images could achieve the benefits of hybrid PET/MRI including superior diagnostics (such as adding PSMA PET to diagnostic paradigms in patients with negative MRI but high degree of clinical suspicion for prostate cancer leading to improved detection) [6,26] and impact on altering management (such as prostatectomy approach and planning including nerve sparing and prediction of positive surgical margins relative to adjacent or at-risk structures) [3,22].