Those inflammatory markers identified in common include IL-1B, TNF-α, IL-6, IL-17, IL-10, IL-4, IL-8, and RANKL [52] Whether variations in the expression of certain biomarkers can be correlated with the future incidence of peri-implant diseases may allow the delineation of a peri-implantitis susceptible patient based on inflammatory profile expressed in the early stages of healing. This evidence concerns the gene IL4 and Peri-Implantitis.