A study conducted in the BiomarCaRE cohort (74,738 participants) revealed significantly higher Abbott hs-cTnI concentrations in individuals with diabetes than in those without [39]; hs-cTnI was also positively associated with systolic blood pressure, left ventricular mass, carotid plaque thickness and correlated negatively with eGFR [39]. This evidence concerns the gene TNNI3 and diabetes mellitus.