NPPB and obesity due to melanocortin 4 receptor deficiency: The hs-cTn concentrations, corresponding to the thresholds for cardiovascular risk stratification (hs-cTn ≥ 5.0 ng/L), were significantly affected by age (>40 years), male sex, obesity, prediabetes, hypertension, elevated BNP concentration (35–99 ng/L), mildly decreased eGFR (60–89 mL/min/1.73 m2) and abnormal TG, LDL-C and non-HDL-C concentrations (significant only for hs-cTnT) (Table 3).