For the following autoantibodies, significant increases between the control group (CTRL) and AMD V7, as well as between AMD V1 and V7, were detected: antibodies targeting the proteins serotransferrin (TF), opioid growth factor receptor (OGFR), 60 kDa chaperonin 2 (groEL2), neurotrophin-4 (NTF4), dermcidin, clusterin (CLUS) and vascular endothelial growth factor (VEGF) (Figure 5 and Figure 6). The gene discussed is CLU; the disease is age-related macular degeneration.