Among the four haplotypes formed by single nucleotide variations of *1b and *5 (OATP1B1*1a (WT), OATP1B1*1b, OATP1B1*5, and OATP1B1*15 (both *1b&*5)) [51], the common variant OATP1B1*5 was highlighted using a GWAS, suggesting an increased risk of simvastatin-induced myopathy in variant carriers [52]. This evidence concerns the gene SLCO1B1 and myopathy.