When comparing RM with PC, we identified key regeneration-related genes APOD and IBSP, along with several significant pathways: cAMP signaling pathway (HHIP), cytokine-cytokine receptor interaction (IL17D), pathways in cancer (HHIP, DAPK2), and biosynthesis of cofactors (RDH12, HAAO). This evidence concerns the gene RDH12 and cancer.