The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and neutrophil high-density lipoprotein ratio (NHR) [18] as well as cytokines released by activated microglia, including TNF-α, IL-1β, and IL-6, are linked to neurodegeneration including atypical parkinsonism disorders like PSP [19]. The gene discussed is IL1B; the disease is supranuclear palsy, progressive, 1.