MT-CO1 and Anxiety: Dataset integration showed that duration in the EPM closed arms correlated with being in the outer zone of the OFT (higher anxiety) and with expression of three hippocampal mitochondrial genes involved in energy metabolism: cytochrome b (Mt-cyb), ATP synthase (Mt-atp6), and cytochrome c oxidase subunit I (Mt-co1), a component of cytochrome c oxidase (Figure 7).