Similarly, the T2DM-ADSCs showed daily fluctuations in PER1, PER2, PER3, CRY1, CRY2, and ARNTL (BMAL1), whereas such fluctuations were not observed in CLOCK1, CLOCK2, CLOCK3, and CLOCK4 (Figure 2a). This evidence concerns the gene PER1 and type 2 diabetes mellitus.