Similarly, in the T2DM-ADSC group, PER1, PER2, PER3, CRY1, CRY2, and ARNTL (BMAL1) showed daily fluctuations, whereas daily fluctuations were not noted for CLOCK1, CLOCK2, CLOCK3, and CLOCK4 (Figure 2b). This evidence concerns the gene BMAL1 and type 2 diabetes mellitus.