This was the case for an AURKA inhibitor that regulates mitotic centrosome maturation and chromosome segregation; an HDAC inhibitor that remodels chromatin structure; three microtubule inhibitors that block mitosis; two platinum-based alkylating agents; and two anti-tumor antibiotics and a topoisomerase inhibitor that interfere with DNA replication and transcription. The gene discussed is AURKA; the disease is neoplasm.