Compared to women with normal pregnancy, those with GDM were slightly older (29.00 (26.00–32.00) vs. 32.00 (29.00–35.00), p = 0.014) and had significantly higher fasting plasma glucose (FPG; fold change (FC) = 1.07), 1 and 2 h plasma glucose concentrations (1 h-PG; FC = 1.20 and 2 h-PG; FC = 1.13, respectively), fasting insulin (FI; FC = 1.82), and values of the homeostasis model assessment for insulin resistance (HOMA-IR) (FC = 1.96; p < 0.001 for all the aforementioned variables), even after adjusting for maternal age (Table S1). The gene discussed is INS; the disease is Insulin resistance.