CRP is an acute-phase reactant that is widely used as a biomarker of inflammation [21], and previous evidence exists in support of its linkage to adiposity and insulin resistance in metabolic disorders [22,23]; however, it is unknown whether changes in postpartum BMI might contribute to alterations in circulating CRP levels and HOMA-IR values in women with GDM in the first year after delivery, and therefore further research is needed to verify this hypothesis. The gene discussed is CRP; the disease is metabolic disease.