A subgroup analysis of the T cell maturation memory state (23 from the ND-AML group, 23 from the CR group, and 8 from the R/R group) revealed a significant decrease in central memory T cells and CD3+, CD4+, and CD8+ T cell subsets in the R/R group (Supplementary Figure S4). Here, CD4 is linked to acute myeloid leukemia.