PLA2G6 and neurodegeneration with brain iron accumulation: A first diagnosis of NBIA was based on the classical “eye of the tiger” sign at Magnetic Resonance Imaging (MRI) analysis, with iron deposits in the globus pallidus, but no pathogenic mutations were found in the main genes involved in the pathology that were at least known at that time (pantothenate kinase2, PANK2; phospholipase A2 group VI, PLA2G6 and FTL).