In this study, we first analyze RNA editing modifications in a panel of eight genes (CAMK1D, GAB2, IFNAR1, KCNJ15, LYN, MDM2, PDE8A, and PRKCB) across four groups of individuals (BD, SZ, SA, and healthy controls) using targeted next-generation sequencing (NGS). This evidence concerns the gene PDE8A and Behcet disease.