The analyses demonstrated that the SNPs rs3757417 T>G and rs12373 A>C in the 3′-UTR of Tyrosylprotein Sulfotransferase 1 (TPST1) and pancreatic adenocarcinoma upregulated factor (PAUF), respectively, are considered potential prognostic markers for patients undergoing surgical resection. The gene discussed is TPST1; the disease is pancreatic adenocarcinoma.