TACSTD2 and head and neck squamous cell carcinoma: As discussed elsewhere [8], in other tumor types beyond those where the ADC has been approved, higher expression of the TAA is also identified, like in BLCA, CESC, HNSCC, LUSC, PAAD, PRAD, and THCA for Trop2 and ESCA and SKCM for Nectin-4 (Figure 1).