IFNG and Right ventricular hypertrophy: These mice displayed IgG and C3 deposition in their kidneys and significantly elevated the serum interferon-gamma (Ifn-γ) and Il-6 levels, along with right ventricular (RV) systolic pressure, right ventricular hypertrophy measured as the Fulton index, ratio of right ventricular weight to the sum of left ventricular (LV) and septal (S) weights (Fulton index = RV/LV + S), and ratio RV weight to whole body weight in comparison to those of wild-type C57BL/6 mice [83,84].