CGAS and neoplasm: Once inside macrophages, miR-25 inhibits the cGAS-STING (Cyclic GMP-AMP synthase–STimulator of INterferon Genes) pathway—a key pathway that promotes the transition of macrophages from an immunosuppressive M2-like phenotype to a pro-inflammatory M1 phenotype needed for effective tumor cell eradication [1,7].