According to Rogeri, C. et al., the hypermethylation of the hsa-miR-124-2, SOX1, TERT, and LMX1A genes could be a promising biomarker for cervical cancer precursor lesions, independent of hr-HPV status, and can be performed with samples collected for cervical cytology and HPV DNA testing. The gene discussed is SOX1; the disease is cervical carcinoma.