mRNA expressions of genes of enzymes with significantly decreased precursor-to-product ratios (i.e., CYP17A1, HSD17B3, CYP11B1 and HSD11B2) was similar in women with preeclampsia and controls, but the RNA levels of these genes were higher in women with preeclampsia (Figure 4). This evidence concerns the gene HSD17B3 and preeclampsia.