UBA1 and inborn error of immunity: Moreover, KEGG analysis (Figure 2D) revealed that UBA1-associated DEGs in BC were involved in xenobiotic metabolism by cytochrome P450 (hsa00980), tyrosine metabolism (hsa00350), chemical carcinogenesis (hsa05204), primary immunodeficiency (hsa05340), drug metabolism-cytochrome P450 (hsa00982), cytokine–cytokine receptor interaction (hsa04060), steroid hormone biosynthesis (hsa00140), nitrogen metabolism (hsa00910), IL-17 signaling pathway (hsa04657), retinol metabolism (hsa00830), and fatty acid degradation (has00071).