BRCA1 and breast cancer: We found evidence of a statistically significant association with breast cancer risk for three genes, with ORs of 16.3 [95% CI: 4.0–66.7] (p = 0.0001) for BRCA1, 12.0 [95% CI: 2.9–45.9] for BRCA2 (p = 0.0001), and 7.3 [95% CI: 0.9–56.7] (p = 0.037) for ATM (Table 2, Figure 2).