This study corroborates our earlier findings, which demonstrated that female Wistar-Kyoto rats with spontaneous hypertension and the retinyl acetate-induced model of detrusor overactivity (DO)—a condition diagnosed in 60–90% of OAB patients—exhibited comparable alterations in calcitonin gene-related peptide (CGRP), OCT3, and VAChT levels, as documented in the research by Wróbel et al. [33]. This evidence concerns the gene SLC22A3 and Hypertension.