Dystrophic neurons and neurites with neurofibrillary tubules have been found to contain phosphorylated active c-Myc protein in a number of neurodegenerative tauopathies, such as AD, Pick’s disease, progressive supranuclear palsy, and cortico-basal degeneration, which is linked to neuronal damage and apoptosis [45,46]. The gene discussed is MYC; the disease is Alzheimer disease.