Meanwhile, the platelet integrin receptor in the form of the GPIb-IX-V complex, consisting of four glycoproteins (GPIbα, GPIbβ, GPIX, and GPV) that constitute the HPA receptor of these cells (Table 1), is abundantly represented on their surface (about 30,000 copies in the form of GPIbβ and GPIX glycoprotein and 15,000 copies in the form of GPV glycoprotein) and, as a result of binding to the PAMP of germs, activates platelet adhesion, as recorded in patients affected by systemic lupus erythematosus (SLE) [6,34]. This evidence concerns the gene GP1BA and systemic lupus erythematosus.