ITGA2B and viral infectious disease: It has been shown that the αIIbβ3 (GPIIb/GPIIIa) platelet receptor, together with the integrin receptor GPIbα and the FcγRIIa receptor (Table 1), when combined with the soluble ligands of these cells, form the most efficient “pathways” to induce platelet activity during bacterial and viral infections [3,5,41,95].