We studied the hypoxia-induced inflammatory response in H358 cells by evaluating IL-6 and IL-8 secretion, as both proinflammatory cytokines have been reported to positively impact the cell proliferation, immune evasion, angiogenesis, and metastatic potential in NSCLC [86,87,88]. This evidence concerns the gene CXCL8 and non-small cell lung carcinoma.