All other CLL-associated NOTCH2 gene variants and SNVs identified in the Spanish WGS dataset together with their frequency (CLL Spain compared to Europe, Africa, East Asia, and Japan), variant allele frequency (VAF), genomic context, gender aspects, and CLL-characteristic NOTCH1 and SF3B1 mutations are summarized in Table S3. This evidence concerns the gene NOTCH2 and B-cell chronic lymphocytic leukemia.