While the role of the FUT10 (UniProtKB-Q6P4F1) isoform in cancer is not yet well-studied, the current findings suggest that as a member of the α-1,3-fucosyltransferase family, it may play an important role not only as a prognostic marker, but also as a potential target for therapeutic interventions in HNCs. Here, POFUT3 is linked to cancer.