The top ten enriched pathways are the complement and coagulation cascades, Apelin signaling pathway, oxytocin signaling pathway, HIF-1 signaling pathway, regulation of actin cytoskeleton, mitophagy-animal, PD-L1 expression and PD-1 checkpoint pathway, transcriptional dysregulation in cancer, focal adhesion, and human papilloma virus infection (HPV). Here, APLN is linked to cancer.