PTK2 and glioblastoma: In our previous studies of activity against glioblastoma cells (line U87MG), we showed that polyphenolic preparations from hawthorn fruit have the ability to promote the cleavage of poly(ADP-ribose) polymerase 1 (PARP1) associated with apoptosis and to inhibit the activity of pro-survival kinases, focal adhesion kinase (FAK), and protein kinase B (PKB), which indicates the suppression of the proliferative and invasive potential of the tested glioblastoma multiforme cells; this effect was associated with the concentration of proanthocyanidins in the preparations [7].