Rivastigmine (marketed under different brand names including ExelonTM, Rivastach® Patch, Prometax®, and SDZ ENA 713) is a reversible inhibitor of both the acetylcholinesterase and butyrylcholinesterase enzymes [27] and is highly effective in the treatment of cognitive decline and Alzheimer’s disease across its mild and moderate stages, as well as in the treatment of various types of dementia including dementia associated with Parkinson’s disease [28,29,30,31,32,33]. This evidence concerns the gene ACHE and Alzheimer disease.