CAP stimulates TRPV1-ribosomal protein 70S6 kinase (TRPV 1-p70S6K) in astrocytes, which activates the p70S6K signaling pathway and promotes the production of endogenous ciliary neurotrophic factor (CNTF), preventing the persistent degeneration of DA in the nigral corpus striatum of rats, which alleviated motor deficits in a rat model of PD. Here, RPS6KB1 is linked to Parkinson disease.