The co-localization of microglia markers and FGF-2 within the CNS has been shown in the murine experimental autoimmune encephalomyelitis (EAE) model of MS by employing antibodies against FGF-2 and microglia-specific fluorescein isothiocyanate-labeled Griffonia simplicifolia isolectin B4 (GS-IB4), as well as antibodies against microglial complement receptor 3 (CR3) [227]. This evidence concerns the gene FGF2 and myeloid sarcoma.