BECN1 and hydrops fetalis: In B6 male mice, supplementation of the HF diet with TC, FO, or their combination resulted in a significant reduction in Beclin1 gene expression compared to the HF group (p < 0.0001) (Figure 11a), and the mRNA levels of Atg5 and Atg12 were slightly decreased by the treatments (Figure 11b,c).