This inhibition was associated with reduced levels of pro-inflammatory cytokines, including interleukin 6 (Il6), tumor necrosis factor-alpha (Tnfα), and interleukin 1beta (Il1β), underscoring the potential of TC extract as a therapeutic intervention for mitigating obesity-induced inflammation [8]. Here, TNF is linked to obesity due to melanocortin 4 receptor deficiency.