With regard to the nutritional status of patients with pancreatic cancer supplemented with omega-3, the most commonly used outcomes for assessing the nutritional status shown in this systematic review includes: weight, body composition, serum albumin, prealbumin, transferrin, ratio EPA/AA, skeletal muscle mass, fat percentage, interleukin-6, BMI, psoas major muscle area (PMA), lymphocytes, total cholesterol, triglycerides, c-reactive protein, HbA1c (%), cortisol, insulin, skinfold arm, back, and iliac crest. This evidence concerns the gene IL6 and pancreatic neoplasm.