SQSTM1 and metabolic dysfunction-associated steatotic liver disease: Reduced levels of BECN1, as well as other proteins, i.e., autophagy-activating kinase Unc-511 (ULK1), p-ULKs555, ATG5, p62/SQSTM1 and BCL2 interacting protein 3 (BNIP3), have been reported in liver samples from MASLD patients compared to control patients with healthy livers, suggesting the impaired initiation of autophagy and autophagosome formation.