Wang et al.’s [7] research also showed that norarecaline has significant anti-anxiety activity, and its mechanism of action is related to combating oxidative stress damage, inhibiting neuroinflammatory response, and regulating neurotransmitter levels and the N-methyl-D-aspartate receptor/calcium–calmodulin-dependent protein kinase II/protein kinase B (NMDAR/CamkII/Akt) signaling pathway. Here, AKT1 is linked to Anxiety.