To further validate the data obtained from examining SIRT2 inhibition in MDA-MB-231 cells, the Human Protein Atlas (www.proteinatlas.org, accessed on date: 13 November 2024) was consulted to identify HCC38 cells, a triple-negative breast cancer (TNBC) cell line exhibiting low SIRT2 expression at the transcriptional level. The gene discussed is SIRT2; the disease is triple-negative breast carcinoma.