In this study, nine pathogenic variants, including three novel variants, were identified in the genes ANK2, MYL2, MYOZ2, MYH7, PTPN11, ACTA2, PRKAG2, and DES, which were considered the cause of disease in patients with DCM and HCM. The gene discussed is ACTA2; the disease is familial dilated cardiomyopathy.