Following these findings, a proposal emerged, suggesting subtyping SCLC into four subtypes defined by the RNA expression of ASCL1, NEUROD1, POU2F3, and YAP1, called SCLC-A, SCLC-N, SCLC-P, and SCLC-Y [22]. The gene discussed is POU2F3; the disease is small cell lung carcinoma.