Studies by Sundquist et al. (2015) [16] and Favaloro et al. (2019) [17] have explored the differential risks associated with various genetic thrombophilias, suggesting that the Prothrombin G20210A mutation may present a slightly lower risk profile compared to Factor V Leiden, but still significantly increases the likelihood of venous thrombosis. The gene discussed is F2; the disease is Venous thrombosis.