PRND and prion disease: Case–controlled studies have identified associations between PRND polymorphisms and prion disease susceptibility in humans at codon 174 and the 3′ untranslated region (UTR) +28 [36,46,47], in cattle at codons 95 and 132 [48], in sheep at codon 26 [49], and in goats at codon 10 [51].