ANXA5 and neoplasm: Significantly more tumor cells were positive for Annexin V, a marker of apoptosis, in the presence of compound plus T-cell compared to compound alone for PTX (p < 0.0001), Bleo (p < 0.0001), Isp (p < 0.0001), and Etop (p < 0.001), confirming the increased T-cell-mediated cytotoxicity observed in the high-throughput assay (Figure 4e,f).