To evaluate the association between the expression of each immunoproteasome subunit and CD8+ T-cell-mediated activity in ccRCC patients, the expression of PSMB8 (LMP7), PSMB9 (LMP2), PSMB10 (MECL-1), CD3E, CD8A, CD8B, and PTPRC (CD45) and estimated CD8+ T cell numbers were obtained from the TCGA database for 531 patients with ccRCC. The gene discussed is CD3E; the disease is nonpapillary renal cell carcinoma.