Taken together, these studies reaffirm our bioinformatics-based analysis and suggest that these extracellular matrix genes (CDH3, COL11A1, COL1A1, COL17A1, KRT19, ITGA2, LAMC2, and SULF1) are highly associated with PDAC tumor carcinogenesis and peritoneal metastasis. Here, COL1A1 is linked to neoplasm.