ABCB1 and neoplasm: Some of the genes are also interesting prospects for their use in therapeutic areas (e.g., MICAL3 for its role in promoting cancer cell migration and invasion, and PTPRU to restore its function as a tumor suppressor), while others are known for their involvement in multidrug resistance in cancer (e.g., CABIN1 and ABCB1) [33,35,36,40,45].