We found that NFKBIA knockdown cells were significantly less sensitive to XPO1-inhibition-mediated cell death in both BT-549 and HCC-1806 with the reported IC50s of knockdown to control being 469 nM to 197 nM (p-value < 0.0001) and 342 nM to 160 nM (p-value < 0.0001), respectively (Figure 6C). The gene discussed is NFKBIA; the disease is hepatocellular carcinoma.