Higher levels of MMP-1 are found in the serum of patients with pancreatic cancer (mean: 8.7 ± 7.5 ng/mL) compared to healthy subjects (mean: 6.7 ± 4.9 ng/mL; p < 0.0001) [23] and in the plasma of patients with lung cancer (median: 1.78 ng/mL) compared to healthy subjects (median: 0.99 ng/mL; p < 0.001) [24]. This evidence concerns the gene MMP1 and pancreatic neoplasm.